MOTS-C 10vials

75.00

MOTS-C (Mitochondrial ORF of the Twelve S rRNA type-C) is a 16-amino-acid peptide encoded within the mitochondrial 12S rRNA gene. Identified in 2015, it functions as a mitochondrial-derived peptide (MDP) involved in regulating metabolic homeostasis. In preclinical and early human studies, MOTS-C enhances insulin sensitivity, promotes lipid and glucose metabolism, and increases exercise capacity. It is supplied as a high-purity lyophilized powder for use in laboratory research. 

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          Description

          All products on this site are for research and development, laboratory, or analytical use only; they are not for human consumption, medical, diagnostic, cosmetic, veterinary, or any other non-research application. The statements and products have not been evaluated by the U.S. Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease. Honest Peptide is not a compounding pharmacy or chemical compounding facility as defined under section 503A of the Federal Food, Drug, and Cosmetic Act, nor an outsourcing facility as defined under section 503B.

           

          Amino Acid Sequence

          Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg

          Molecular Formula

          C₁₀₁H₁₅₂N₂₈O₂₂S₂

          Molecular Weight

          2174.6 g/mol

          PubChem CID

          146675088

          CAS Number

          1627580-64-6

          Vial Size

          3ml

          Contents

          Lyophilized powder, white/off-white color
           

          Mechanism of action

          AMPK Activation

          MOTS-C increases levels of AICAR and stimulates AMPK, leading to enhanced glucose uptake and fatty-acid oxidation.

          Insulin Sensitivity

          Improves glucose tolerance and insulin action in diet-induced obese mice; correlates with insulin signaling enhancement in skeletal muscle.

          Exercise Mimetic Role

          Circulating MOTS-C rises in humans during acute exercise; in mice, administration increases exercise performance and stress adaptation.

          Cytoprotection

          Acts as a “mitokine,” transmitting mitochondrial stress signals and promoting cellular resilience.
           

          Storage & handling

          Storage:

          Store the lyophilized vial in a cool, dry area protected from direct sunlight.